Electron Detachment Dissociation for Top‐Down Mass Spectrometry of Acidic Proteins
نویسندگان
چکیده
منابع مشابه
Electron Detachment Dissociation for Top-Down Mass Spectrometry of Acidic Proteins
Electron detachment dissociation (EDD) is an emerging mass spectrometry (MS) technique for the primary structure analysis of peptides, carbohydrates, and oligonucleotides. Herein, we explore the potential of EDD for sequencing of proteins of up to 147 amino acid residues by using top-down MS. Sequence coverage ranged from 72% for Melittin, which lacks carboxylic acid functionalities, to 19% for...
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ژورنال
عنوان ژورنال: Chemistry – A European Journal
سال: 2011
ISSN: 0947-6539,1521-3765
DOI: 10.1002/chem.201003709